SCN8A Rabbit pAb (APR17641N)

Product Specifications

Background

This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SCN8A Rabbit pAb (APR17641N) .

Synonyms

SCN8A; BFIS5; CERIII; CIAT; EIEE13; MED; NaCh6; Nav1.6; PN4

Gene ID

6334

UniProt

Q9UQD0

Cellular Locus

Cytoplasmic vesicle, Membrane, Multi-pass membrane protein

Dilution

WB 1:200 - 1:1000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 145kDa/220kDa/225kDa/226kDa Observed MW: 165kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.