SCN8A Rabbit pAb (APR17641N)
Product Specifications
Background
This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.
Synonyms
SCN8A; BFIS5; CERIII; CIAT; EIEE13; MED; NaCh6; Nav1.6; PN4
Gene ID
6334
UniProt
Q9UQD0
Cellular Locus
Cytoplasmic vesicle, Membrane, Multi-pass membrane protein
Dilution
WB 1:200 - 1:1000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 145kDa/220kDa/225kDa/226kDa Observed MW: 165kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SCN8A Rabbit pAb (APR17641N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6334
Uniprot URL
https://www.uniprot.org/uniprot/Q9UQD0
AA Sequence
AGKYHYCFNETSEIRFEIEDVNNKTECEKLMEGNNTEIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPKYEDNIYM
Available Sizes
Curated Selection
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