EAAT2/SLC1A2 Rabbit pAb (APR17582N)
Product Specifications
Background
This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EAAT2/SLC1A2 Rabbit pAb (APR17582N) .
Synonyms
SLC1A2; EAAT2; EIEE41; GLT-1; HBGT
Gene ID
6506
UniProt
P43004
Cellular Locus
Membrane, Multi-pass membrane protein
Applications
WB (Rattus norvegicus, Mus musculus)
Dilution
WB 1:500 - 1:5000 IHC 1:100 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 61kDa/62kDa Observed MW: 65kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6506
Uniprot URL
https://www.uniprot.org/uniprot/P43004
AA Sequence
HLSKSELDTIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEPWKREK
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