Bak Rabbit pAb (APR17459N)
Product Specifications
Background
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Bak Rabbit pAb (APR17459N) .
Synonyms
BAK1; BAK; BAK-LIKE; BCL2L7
Gene ID
578
UniProt
Q16611
Cellular Locus
Mitochondrion membrane, Single-pass membrane protein
Applications
WB (Homo sapiens, Mus musculus) IP (Homo sapiens, Mus musculus)
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:100
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 16kDa/23kDa Observed MW: 23kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=578
Uniprot URL
https://www.uniprot.org/uniprot/Q16611
AA Sequence
Email for sequence
Available Sizes
Frequently Asked Questions
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