EIF4E Rabbit pAb (APR17455N)
Product Specifications
Background
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality eIF4E Rabbit pAb (APR17455N) .
Synonyms
AUTS19; CBP; EIF4E1; EIF4EL1; EIF4F; eIF-4E; EIF4E
Gene ID
1977
UniProt
P06730
Cellular Locus
Cytoplasm, P-body
Dilution
WB 1:500 - 1:2000 IF 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 25kDa/27kDa/28kDa Observed MW: 24kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1977
Uniprot URL
https://www.uniprot.org/uniprot/P06730
AA Sequence
MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS8422664-01 0.12 mL
Rabbit Anti ATP4B Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3)(IHC)
Sign In for Pricing
View Details MBS8422664-02 0.2 mL
Rabbit Anti ATP4B Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3)(IHC)
Sign In for Pricing
View Details MBS8422664-03 5x 0.2 mL
Rabbit Anti ATP4B Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3)(IHC)
Sign In for Pricing
View Details 
B0807-12Q-Biotin 100 µL
Bcl 10 (B Cell Lymphoma/leukemia 10, B cell CLL/lymphoma 10, CARD Containing Apoptotic Signaling Protein, CARD-containing Molecule Enhancing NF kappa B, CARD Containing Molecule Enhancing NFkB, CARD-containing Molecule Enhancing NF-kB, CARMEN, cCARMEN, CARD-containing Proapoptotic Protein, CARD-like Apoptotic Protein, CLAP, Caspase Recruiting Domain Containing Protein, CED-3/ICH-1 Prodomain Homologous E10-like Regulator, CIPER, Cellular E10, c E10, c-E10, Cellular Homolog of vCARMEN, hCLAP, Mammalian CARD Containing Adapter Molecule E10, mE10) (Biotin) discontinued
Sign In for Pricing
View Details