PPARγ Rabbit pAb (APR17384N)
Product Specifications
Background
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PPARγ Rabbit pAb (APR17384N) .
Synonyms
CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma; PPAR gamma; PPARG
Gene ID
5468
UniProt
P37231
Cellular Locus
Cytoplasm, Nucleus
Applications
IHC (Mouse Embryonic Stem Cells, Mus musculus, Rattus norvegicus) WB (Human liver cell, Homo sapiens, Mus musculus, Rattus norvegicus, Melodinus cochinchinensis, Mesocricetus auratus, Sus scrofa) IF (Homo sapiens)
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 21kDa/54kDa/57kDa Observed MW: 57KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5468
Uniprot URL
https://www.uniprot.org/uniprot/P37231
AA Sequence
LSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFH
Available Sizes
Curated Selection
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