What is the catalog number for SPHK1 Rabbit pAb (APR17308N)?

The catalog number for SPHK1 Rabbit pAb (APR17308N) is APR17308N.

What sizes are available for SPHK1 Rabbit pAb (APR17308N)?

SPHK1 Rabbit pAb (APR17308N) is available in the following size(s): 50 µL, 100 µL, 200 µL.

How many pack sizes does SPHK1 Rabbit pAb (APR17308N) come in?

SPHK1 Rabbit pAb (APR17308N) is available in 3 different pack sizes.

Is SPHK1 Rabbit pAb (APR17308N) in stock?

SPHK1 Rabbit pAb (APR17308N) is currently made to order / not held in immediate stock. Contact us for lead time.

SPHK1 Rabbit pAb (APR17308N)

Product Specifications

Background

The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPHK1 Rabbit pAb (APR17308N) .

Synonyms

SPHK1; SPHK

Gene ID

8877

UniProt

Q9NYA1

Cellular Locus

Cell membrane, Cytoplasm, Nucleus

Applications

WB (Rattus norvegicus)

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 42kDa/43kDa/51kDa Observed MW: 55kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8877

Uniprot URL

https://www.uniprot.org/uniprot/Q9NYA1

AA Sequence

TLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRRLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPASPVVVQQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSGCVEPPPSWKPQQMPPPEEPL