Phospho-Smad3-S423/S425 Rabbit mAb (AMR13085N)
Product Specifications
Background
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]
Synonyms
HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3; SMAD3
Gene ID
4088
UniProt
P84022
Cellular Locus
Cytoplasm, Nucleus
Applications
WB (Mus musculus, Rattus norvegicus, Homo sapiens) IHC (Mus musculus)
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 48kDa Observed MW: 55KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-Smad3-S423/S425 Rabbit mAb (AMR13085N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4088
Uniprot URL
https://www.uniprot.org/uniprot/P84022
AA Sequence
Email for sequence
Available Sizes
Curated Selection
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