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IL2 Rabbit mAb (AMR12852N)

Product Specifications

Background

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7) . The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL2 Rabbit mAb (APR24550N4) .

Synonyms

IL2; IL-2; TCGF; lymphokine

Gene ID

3558

UniProt

P60568

Cellular Locus

Secreted

Dilution

ELISA 1:500 - 1:2000 WB 1:500 - 1:2000 FC 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% Thimerosal, pH7.3.

Molecular Weight

Calculated MW: 17kDa Observed MW: 14KDa/15KDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3558

Uniprot URL

https://www.uniprot.org/uniprot/P60568

AA Sequence

Email for sequence

Available Sizes

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