CHMP2B Rabbit mAb (AMR11590N)
Product Specifications
Background
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CHMP2B Rabbit mAb (APR24467N4) .
Synonyms
CHMP2B; ALS17; CHMP2.5; DMT1; VPS2-2; VPS2B; charged multivesicular body protein 2b
Gene ID
25978
UniProt
Q9UQN3
Cellular Locus
Cytoplasm, Late endosome membrane, Peripheral membrane protein, cytosol
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 28kDa Observed MW: 28KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=25978
Uniprot URL
https://www.uniprot.org/uniprot/Q9UQN3
AA Sequence
Email for sequence
Available Sizes
Frequently Asked Questions
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