CD70 Rabbit mAb (AMR11437N)
Product Specifications
Background
CD70 is a member of the TNF family whose expression is upregulated on DCs upon maturation. Its only receptor, CD27, is expressed on T cells and NK cells. The CD70/CD27 pathway promotes effector CD8+ T cells responses (by sustaining survival of CTLs) and influences polarization of CD4+ T cells, as it represents an alternative IL-12-independent pathway of Th1 priming and suppresses effector Th17 function.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD70 Rabbit mAb (APR24584N9) .
Gene ID
970
UniProt
P32970
Dilution
WB 1:500 - 1:2000 FC 1:100 - 1:800
Form
Liquid
Buffer
Buffer: PBS with 0.02% thimerosal, pH7.4.
Molecular Weight
Observed MW: Refer to figures
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=970
Uniprot URL
https://www.uniprot.org/uniprot/P32970
AA Sequence
Email for sequence
Available Sizes
Frequently Asked Questions
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