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CD70 Rabbit mAb (AMR11437N)

Product Specifications

Background

CD70 is a member of the TNF family whose expression is upregulated on DCs upon maturation. Its only receptor, CD27, is expressed on T cells and NK cells. The CD70/CD27 pathway promotes effector CD8+ T cells responses (by sustaining survival of CTLs) and influences polarization of CD4+ T cells, as it represents an alternative IL-12-independent pathway of Th1 priming and suppresses effector Th17 function.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD70 Rabbit mAb (APR24584N9) .

Gene ID

970

UniProt

P32970

Dilution

WB 1:500 - 1:2000 FC 1:100 - 1:800

Form

Liquid

Buffer

Buffer: PBS with 0.02% thimerosal, pH7.4.

Molecular Weight

Observed MW: Refer to figures

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=970

Uniprot URL

https://www.uniprot.org/uniprot/P32970

AA Sequence

Email for sequence

Available Sizes

Frequently Asked Questions

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