TUG/ASPSCR1 Rabbit mAb (AMR11355N)

Product Specifications

Background

The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4) . This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t (X;17) (p11; q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TUG/ASPSCR1 Rabbit mAb (AMR11355N) .

Synonyms

ASPSCR1; ASPCR1; ASPL; ASPS; RCC17; TUG; UBXD9; UBXN9; tether containing UBX domain for GLUT4

Gene ID

79058

UniProt

Q9BZE9

Cellular Locus

Cytoplasm, Endomembrane system, Endoplasmic reticulum-Golgi intermediate compartment membrane, Nucleus, Peripheral membrane protein

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 70-80kDa Observed MW: 75KDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.