Phospho-YAP1-S127 Rabbit pAb (AMR00938N)

Product Specifications

Background

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-YAP1-S127 Rabbit pAb (AMR00938N) .

Synonyms

COB1; YAP; YAP2; YAP65; YKI; YAP1

Gene ID

10413

UniProt

P46937

Cellular Locus

Cytoplasm, Nucleus

Applications

WB (THP1, Homo sapiens, Mus musculus, Rattus norvegicus)

Dilution

WB 1:500 - 1:1000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 36kDa/48kDa/49kDa/50kDa/52kDa/53kDa/54kDa Observed MW: 68kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.