Phospho-YAP1-S127 Rabbit pAb (AMR00938N)
Product Specifications
Background
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms
COB1; YAP; YAP2; YAP65; YKI; YAP1
Gene ID
10413
UniProt
P46937
Cellular Locus
Cytoplasm, Nucleus
Applications
WB (THP1, Homo sapiens, Mus musculus, Rattus norvegicus)
Dilution
WB 1:500 - 1:1000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 36kDa/48kDa/49kDa/50kDa/52kDa/53kDa/54kDa Observed MW: 68kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-YAP1-S127 Rabbit pAb (AMR00938N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10413
Uniprot URL
https://www.uniprot.org/uniprot/P46937
AA Sequence
AHSSP
Available Sizes
Curated Selection
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