Phospho-GRIN2B-Y1474 Rabbit pAb (AMR00905N)
Product Specifications
Background
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B) . The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
Synonyms
GRIN2B; EIEE27; GluN2B; MRD6; NMDAR2B; NR2B; hNR3
Gene ID
2904
UniProt
Q13224
Cellular Locus
Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 166kDa Observed MW: 200kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-GRIN2B-Y1474 Rabbit pAb (AMR00905N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2904
Uniprot URL
https://www.uniprot.org/uniprot/Q13224
AA Sequence
Email for sequence
Available Sizes
Curated Selection
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