Phospho-STAT1-Y701 Rabbit pAb (AMR00853N)
Product Specifications
Background
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-STAT1-Y701 Rabbit pAb (AMR00853N) .
Synonyms
CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91; STAT1 alpha; STAT1
Gene ID
6772
UniProt
P42224
Cellular Locus
Cytoplasm, Nucleus
Applications
WB (Human chronic myeloid leukemia cells, Mus musculus, Homo sapiens) IP (Mus musculus)
Dilution
WB 1:500 - 1:1000 IHC 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 83kDa/87kDa Observed MW: 84KDa/91KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6772
Uniprot URL
https://www.uniprot.org/uniprot/P42224
AA Sequence
Email for sequence
Available Sizes
Frequently Asked Questions
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