Phospho-BTK-Y223 Rabbit pAb (AMR00846N)

Product Specifications

Background

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-BTK-Y223 Rabbit pAb (AMR00846N) .

Synonyms

AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA; BTK

Gene ID

695

UniProt

Q06187

Cellular Locus

Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein

Applications

WB (Mus musculus, Rattus norvegicus)

Dilution

WB 1:500 - 1:2000 IF 1:20 - 1:100

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 76kDa/79kDa Observed MW: Refer to Figures

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.