Phospho-BTK-Y223 Rabbit pAb (AMR00846N)
Product Specifications
Background
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms
AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA; BTK
Gene ID
695
UniProt
Q06187
Cellular Locus
Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein
Applications
WB (Mus musculus, Rattus norvegicus)
Dilution
WB 1:500 - 1:2000 IF 1:20 - 1:100
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 76kDa/79kDa Observed MW: Refer to Figures
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-BTK-Y223 Rabbit pAb (AMR00846N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=695
Uniprot URL
https://www.uniprot.org/uniprot/Q06187
AA Sequence
ALYDY
Available Sizes
Curated Selection
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