Phospho-mTOR-S2448 Rabbit pAb (AMR00842N)
Product Specifications
Background
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-mTOR-S2448 Rabbit pAb (AMR00842N) .
Synonyms
FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS; mTOR; MTOR
Gene ID
2475
UniProt
P42345
Cellular Locus
Cytoplasm, Cytoplasmic side, Endoplasmic reticulum membrane, Golgi apparatus membrane, Lysosome, Mitochondrion outer membrane, Nucleus, PML body, Peripheral membrane protein
Applications
WB (H460, Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa, Capra hircus, Macaca mulatta)
Dilution
WB 1:500 - 1:2000 IF 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 288kDa Observed MW: 289KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2475
Uniprot URL
https://www.uniprot.org/uniprot/P42345
AA Sequence
TDSYS
Available Sizes
Frequently Asked Questions
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