[KO Validated] AKT2 Rabbit pAb (AMM08802N)
Product Specifications
Background
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] AKT2 Rabbit pAb (AMM08802N) .
Synonyms
AKT2; HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA
Gene ID
208
UniProt
P31751
Cellular Locus
Cell membrane, Cytoplasm, Early endosome, Nucleus, Peripheral membrane protein
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:100 ICC 1:50 - 1:200 IF 1:50 - 1:100 IP 1:20 - 1:50 ChIP 1:20 - 1:100
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 51kDa/55kDa Observed MW: 60kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=208
Uniprot URL
https://www.uniprot.org/uniprot/P31751
AA Sequence
Email for sequence
Available Sizes
Frequently Asked Questions
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