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[KO Validated] AKT2 Rabbit pAb (AMM08802N)

Product Specifications

Background

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] AKT2 Rabbit pAb (AMM08802N) .

Synonyms

AKT2; HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA

Gene ID

208

UniProt

P31751

Cellular Locus

Cell membrane, Cytoplasm, Early endosome, Nucleus, Peripheral membrane protein

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 ICC 1:50 - 1:200 IF 1:50 - 1:100 IP 1:20 - 1:50 ChIP 1:20 - 1:100

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 51kDa/55kDa Observed MW: 60kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=208

Uniprot URL

https://www.uniprot.org/uniprot/P31751

AA Sequence

Email for sequence

Available Sizes

Frequently Asked Questions

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