IL17 (IL17A) Mouse Monoclonal Antibody [Clone ID: LBI12H7]
Product Specifications
Background
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) . High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
Synonyms
CTLA-8; CTLA8; IL-17; IL-17A; IL17; ILA17
Gene Name
Homo sapiens interleukin 17A (IL17A), mRNA.
Gene ID
3605
UniProt
Q16552
Conjugation
Unconjugated
Related Pathways
Cytokine-cytokine receptor interaction
Field of Research
Cytokine-cytokine receptor interaction
Dilution
ELISA 1:5000-10000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Secreted Protein
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
IL17A
Overview
Carrier-free (BSA/glycerol-free) IL-17A mouse monoclonal antibody, clone LBI12H7
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3605
Uniprot URL
https://www.uniprot.org/uniprot/Q16552
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