IL17 (IL17A) Mouse Monoclonal Antibody [Clone ID: LBI3D5]

Product Specifications

Background

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) . High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) IL-17A mouse monoclonal antibody, clone LBI3D5

Synonyms

CTLA-8; CTLA8; IL-17; IL-17A; IL17; ILA17

Gene Name

Homo sapiens interleukin 17A (IL17A), mRNA.

Gene ID

3605

UniProt

Q16552

Conjugation

Unconjugated

Related Pathways

Cytokine-cytokine receptor interaction

Field of Research

Cytokine-cytokine receptor interaction

Dilution

ELISA 1:5000-10000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Secreted Protein

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.