MYBPC3 Mouse Monoclonal Antibody [Clone ID: LBI7C8]
Product Specifications
Background
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
Synonyms
CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C
Gene Name
Homo sapiens myosin binding protein C3 (MYBPC3), mRNA.
Gene ID
4607
UniProt
Q14896
Conjugation
Unconjugated
Related Pathways
Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
Field of Research
Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
Dilution
ELISA 1:5000-10000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
MYBPC3
Overview
Carrier-free (BSA/glycerol-free) MYBPC3 mouse monoclonal antibody, clone LBI7C8
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4607
Uniprot URL
https://www.uniprot.org/uniprot/Q14896
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