MYBPC3 Mouse Monoclonal Antibody [Clone ID: LBI3E2]

Product Specifications

Background

MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) MYBPC3 mouse monoclonal antibody, clone LBI3E2

Synonyms

CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C

Gene Name

Homo sapiens myosin binding protein C3 (MYBPC3), mRNA.

Gene ID

4607

UniProt

Q14896

Conjugation

Unconjugated

Related Pathways

Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Field of Research

Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Dilution

ELISA 1:5000-10000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.