Collagen VI (COL6A1) Mouse Monoclonal Antibody [Clone ID: LBI1G8]
Product Specifications
Background
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1 (VI), alpha2 (VI), and alpha3 (VI) chains. The alpha2 (VI) and alpha3 (VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1 (VI) chain) . Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008]
Synonyms
BTHLM1; OPLL; UCHMD1
Gene Name
Homo sapiens collagen type VI alpha 1 chain (COL6A1), mRNA.
Gene ID
1291
UniProt
P12109
Conjugation
Unconjugated
Related Pathways
ECM-receptor interaction, Focal adhesion
Field of Research
ECM-receptor interaction, Focal adhesion
Dilution
WB 1:500
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
COL6A1
Overview
Carrier-free (BSA/glycerol-free) COL6A1 mouse monoclonal antibody, clone LBI1G8
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1291
Uniprot URL
https://www.uniprot.org/uniprot/P12109
Curated Selection
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