Collagen VI (COL6A1) Mouse Monoclonal Antibody [Clone ID: LBI1G8]

Product Specifications

Background

The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1 (VI), alpha2 (VI), and alpha3 (VI) chains. The alpha2 (VI) and alpha3 (VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1 (VI) chain) . Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) COL6A1 mouse monoclonal antibody, clone LBI1G8

Synonyms

BTHLM1; OPLL; UCHMD1

Gene Name

Homo sapiens collagen type VI alpha 1 chain (COL6A1), mRNA.

Gene ID

1291

UniProt

P12109

Conjugation

Unconjugated

Related Pathways

ECM-receptor interaction, Focal adhesion

Field of Research

ECM-receptor interaction, Focal adhesion

Dilution

WB 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.