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CREM Mouse Monoclonal Antibody [Clone ID: LBI6H4]

Product Specifications

Background

This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) CREM mouse monoclonal antibody, clone LBI6H4

Synonyms

CREM-2; hCREM-2; ICER

Gene Name

Homo sapiens cAMP responsive element modulator (CREM), transcript variant 6, mRNA.

Gene ID

1390

UniProt

Q03060

Conjugation

Unconjugated

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

CREM

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=1390

Uniprot URL

https://www.uniprot.org/uniprot/Q03060

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