GLI1 Mouse Monoclonal Antibody [Clone ID: LBI4E2]
Product Specifications
Background
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Overview
Carrier-free (BSA/glycerol-free) GLI1 mouse monoclonal antibody, clone LBI4E2
Synonyms
GLI; PAPA8; PPD1
Gene Name
Homo sapiens GLI family zinc finger 1 (GLI1), transcript variant 1, mRNA.
Gene ID
2735
UniProt
P08151
Conjugation
Unconjugated
Related Pathways
Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer
Field of Research
Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
GLI1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2735
Uniprot URL
https://www.uniprot.org/uniprot/P08151
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