ACE2 Mouse Monoclonal Antibody [Clone ID: LBI4C5] (Angiotensin Converting Enzyme 2)

Product Specifications

Background

The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) ACE2 mouse monoclonal antibody, clone LBI4C5

Synonyms

ACEH

Gene Name

Homo sapiens angiotensin converting enzyme 2 (ACE2), transcript variant 2, mRNA.

Gene ID

59272

UniProt

Q9BYF1

Conjugation

Unconjugated

Related Pathways

Renin-angiotensin system

Field of Research

Renin-angiotensin system

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Secreted Protein, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.