Acid sphingomyelinase (SMPD1) Mouse Monoclonal Antibody [Clone ID: LBI3H7]

Product Specifications

Background

The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB) . Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]

Overview

Carrier-free (BSA/glycerol-free) SMPD1 mouse monoclonal antibody, clone LBI3H7

Synonyms

ASM; ASMASE; NPD

Gene Name

Homo sapiens sphingomyelin phosphodiesterase 1 (SMPD1), transcript variant 1, mRNA.

Gene ID

6609

UniProt

P17405

Conjugation

Unconjugated

Related Pathways

Lysosome, Metabolic pathways, Sphingolipid metabolism

Field of Research

Lysosome, Metabolic pathways, Sphingolipid metabolism

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.