Acid sphingomyelinase (SMPD1) Mouse Monoclonal Antibody [Clone ID: LBI3H7]
Product Specifications
Background
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB) . Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]
Overview
Carrier-free (BSA/glycerol-free) SMPD1 mouse monoclonal antibody, clone LBI3H7
Synonyms
ASM; ASMASE; NPD
Gene Name
Homo sapiens sphingomyelin phosphodiesterase 1 (SMPD1), transcript variant 1, mRNA.
Gene ID
6609
UniProt
P17405
Conjugation
Unconjugated
Related Pathways
Lysosome, Metabolic pathways, Sphingolipid metabolism
Field of Research
Lysosome, Metabolic pathways, Sphingolipid metabolism
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SMPD1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6609
Uniprot URL
https://www.uniprot.org/uniprot/P17405
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