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DDOST Mouse Monoclonal Antibody [Clone ID: LBI2B4]

Product Specifications

Background

This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]

Synonyms

AGER1; CDG1R; OKSWcl45; OST; OST48; WBP1

Gene Name

Homo sapiens dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit (DDOST), mRNA.

Gene ID

1650

UniProt

P39656

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, N-Glycan biosynthesis

Field of Research

Metabolic pathways, N-Glycan biosynthesis

Dilution

WB 1:500, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

DDOST

Overview

Carrier-free (glycerol/BSA-free) DDOST mouse monoclonal antibody, clone LBI2B4

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=1650

Uniprot URL

https://www.uniprot.org/uniprot/P39656

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