PDE1A Mouse Monoclonal Antibody [Clone ID: LBI7D5]
Product Specifications
Background
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca (2+) /calmodulin (see CALM1; MIM 114180) -dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca (2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]) . [supplied by OMIM, Oct 2009]
Synonyms
CAM-PDE-1A; HCAM-1; HCAM1; HSPDE1A
Gene Name
Homo sapiens phosphodiesterase 1A (PDE1A), transcript variant 1, mRNA.
Gene ID
5136
UniProt
P54750
Conjugation
Unconjugated
Related Pathways
Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism, Taste transduction
Field of Research
Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism, Taste transduction
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PDE1A
Overview
Carrier-free (BSA/glycerol-free) PDE1A mouse monoclonal antibody, clone LBI7D5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5136
Uniprot URL
https://www.uniprot.org/uniprot/P54750
Curated Selection
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