BMP4 Mouse Monoclonal Antibody [Clone ID: LBI1D1]
Product Specifications
Background
This gene encodes a member of the bone morphogenetic protein (BMP) family of proteins, which is part of the transforming growth factor-beta (TGF-beta) superfamily. Members of the BMP family play an important role in bone and cartilage development. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Synonyms
BMP2B; BMP2B1; MCOPS6; OFC11; ZYME
Gene Name
Homo sapiens bone morphogenetic protein 4 (BMP4), transcript variant 1, mRNA.
Gene ID
652
UniProt
P12644
Conjugation
Unconjugated
Related Pathways
Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, TGF-beta signaling pathway
Field of Research
Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, TGF-beta signaling pathway
Dilution
WB 1:500
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
BMP4
Overview
Carrier-free (BSA/glycerol-free) BMP4 mouse monoclonal antibody, clone LBI1D1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=652
Uniprot URL
https://www.uniprot.org/uniprot/P12644
Curated Selection
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