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CD63 Mouse Monoclonal Antibody [Clone ID: LBI5E5]

Product Specifications

Background

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]

Synonyms

LAMP-3; ME491; MLA1; OMA81H; TSPAN30

Gene Name

Homo sapiens CD63 molecule (CD63), transcript variant 1, mRNA.

Gene ID

967

UniProt

P08962

Conjugation

Unconjugated

Related Pathways

Lysosome

Field of Research

Lysosome

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

CD63

Overview

Carrier-free (BSA/glycerol-free) CD63 mouse monoclonal antibody, clone LBI5E5

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=967

Uniprot URL

https://www.uniprot.org/uniprot/P08962

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