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UBE2B Mouse Monoclonal Antibody [Clone ID: LBI1E11]

Product Specifications

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) UBE2B mouse monoclonal antibody, clone LBI1E11

Synonyms

E2-17kDa; HHR6B; HR6B; RAD6B; UBC2

Gene Name

Homo sapiens ubiquitin conjugating enzyme E2 B (UBE2B), mRNA.

Gene ID

7320

UniProt

P63146

Conjugation

Unconjugated

Related Pathways

Ubiquitin mediated proteolysis

Field of Research

Ubiquitin mediated proteolysis

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

UBE2B

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=7320

Uniprot URL

https://www.uniprot.org/uniprot/P63146

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