GBA Mouse Monoclonal Antibody [Clone ID: LBI2C12]
Product Specifications
Background
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Synonyms
GBA1; GCB; GLUC
Gene Name
Homo sapiens glucosylceramidase beta (GBA), transcript variant 1, mRNA.
Gene ID
2629
UniProt
P04062
Conjugation
Unconjugated
Related Pathways
Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism
Field of Research
Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism
Dilution
WB 1:2000, IHC 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
GBA
Overview
Carrier-free (BSA/glycerol-free) GBA mouse monoclonal antibody, clone LBI2C12
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2629
Uniprot URL
https://www.uniprot.org/uniprot/P04062
Curated Selection
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