IL1RA (IL1RN) Mouse Monoclonal Antibody [Clone ID: LBI2B1]
Product Specifications
Background
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Synonyms
DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4
Gene Name
Homo sapiens interleukin 1 receptor antagonist (IL1RN), transcript variant 4, mRNA.
Gene ID
3557
UniProt
P18510
Conjugation
Unconjugated
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Secreted Protein
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
IL1RN
Overview
Carrier-free (BSA/glycerol-free) IL1RN mouse monoclonal antibody, clone LBI2B1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3557
Uniprot URL
https://www.uniprot.org/uniprot/P18510
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