HMBS Mouse Monoclonal Antibody [Clone ID: LBI3E2]
Product Specifications
Background
This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Overview
Carrier-free (BSA/glycerol-free) HMBS mouse monoclonal antibody, clone LBI3E2
Synonyms
PBG-D; PBGD; PORC; UPS
Gene Name
Homo sapiens hydroxymethylbilane synthase (HMBS), transcript variant 1, mRNA.
Gene ID
3145
UniProt
P08397
Conjugation
Unconjugated
Related Pathways
Metabolic pathways, Porphyrin and chlorophyll metabolism
Field of Research
Metabolic pathways, Porphyrin and chlorophyll metabolism
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
HMBS
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3145
Uniprot URL
https://www.uniprot.org/uniprot/P08397
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