Ornithine Carbamoyltransferase (OTC) Mouse Monoclonal Antibody [Clone ID: LBI5E4]

Product Specifications

Background

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) OTC mouse monoclonal antibody, clone LBI5E4

Synonyms

OCTD; OTCD

Gene Name

Homo sapiens ornithine transcarbamylase (OTC), mRNA; nuclear gene for mitochondrial product.

Gene ID

5009

UniProt

P00480

Conjugation

Unconjugated

Related Pathways

Arginine and proline metabolism, Metabolic pathways

Field of Research

Arginine and proline metabolism, Metabolic pathways

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.