DDIT3 Mouse Monoclonal Antibody [Clone ID: LBI4C4]
Product Specifications
Background
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]
Synonyms
CEBPZ; CHOP; CHOP-10; CHOP10; GADD153
Gene Name
Homo sapiens DNA damage inducible transcript 3 (DDIT3), transcript variant 5, mRNA.
Gene ID
1649
UniProt
P35638
Conjugation
Unconjugated
Related Pathways
MAPK signaling pathway
Field of Research
MAPK signaling pathway
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
DDIT3
Overview
Carrier-free (BSA/glycerol-free) DDIT3 mouse monoclonal antibody, clone LBI4C4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1649
Uniprot URL
https://www.uniprot.org/uniprot/P35638
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
