NUMB Mouse Monoclonal Antibody [Clone ID: LBI3B2]
Product Specifications
Background
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
C14orf41; c14_5527; S171
Gene Name
Homo sapiens NUMB endocytic adaptor protein (NUMB), transcript variant 2, mRNA.
Gene ID
8650
UniProt
P49757
Conjugation
Unconjugated
Related Pathways
Notch signaling pathway
Field of Research
Notch signaling pathway
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NUMB
Overview
Carrier-free (BSA/glycerol-free) NUMB mouse monoclonal antibody, clone LBI3B2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8650
Uniprot URL
https://www.uniprot.org/uniprot/P49757
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