CD30 (TNFRSF8) Mouse Monoclonal Antibody [Clone ID: LBI4B3]
Product Specifications
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Synonyms
CD30; D1S166E; Ki-1
Gene Name
Homo sapiens TNF receptor superfamily member 8 (TNFRSF8), transcript variant 1, mRNA.
Gene ID
943
UniProt
P28908
Conjugation
Unconjugated
Related Pathways
Cytokine-cytokine receptor interaction
Field of Research
Cytokine-cytokine receptor interaction
Dilution
WB 1:2000, FLOW 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
TNFRSF8
Overview
Carrier-free (BSA/glycerol-free) TNFRSF8 mouse monoclonal antibody, clone LBI4B3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=943
Uniprot URL
https://www.uniprot.org/uniprot/P28908
Curated Selection
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