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DOCK8 Mouse Monoclonal Antibody [Clone ID: LBI1E11]

Product Specifications

Background

This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]

Overview

Carrier-free (BSA/glycerol-free) DOCK8 mouse monoclonal antibody, clone LBI1E11

Synonyms

HEL-205; MRD2; ZIR8

Gene Name

Homo sapiens dedicator of cytokinesis 8 (DOCK8), transcript variant 1, mRNA.

Gene ID

81704

UniProt

Q8NF50

Conjugation

Unconjugated

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

DOCK8

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=81704

Uniprot URL

https://www.uniprot.org/uniprot/Q8NF50

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