Neuraminidase (NEU1) Mouse Monoclonal Antibody [Clone ID: LBI3D4]
Product Specifications
Background
The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein') . Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008]
Synonyms
NANH; NEU; SIAL1
Gene Name
Homo sapiens neuraminidase 1 (NEU1), mRNA.
Gene ID
4758
UniProt
Q99519
Conjugation
Unconjugated
Related Pathways
Lysosome, Other glycan degradation, Sphingolipid metabolism
Field of Research
Lysosome, Other glycan degradation, Sphingolipid metabolism
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NEU1
Overview
Carrier-free (BSA/glycerol-free) NEU1 mouse monoclonal antibody, clone LBI3D4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4758
Uniprot URL
https://www.uniprot.org/uniprot/Q99519
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items