CD30 (TNFRSF8) Mouse Monoclonal Antibody [Clone ID: LBI1C6]

Product Specifications

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) TNFRSF8 mouse monoclonal antibody, clone LBI1C6

Synonyms

CD30; D1S166E; Ki-1

Gene Name

Homo sapiens TNF receptor superfamily member 8 (TNFRSF8), transcript variant 1, mRNA.

Gene ID

943

UniProt

P28908

Conjugation

Unconjugated

Related Pathways

Cytokine-cytokine receptor interaction

Field of Research

Cytokine-cytokine receptor interaction

Dilution

WB 1:2000, IHC 1:150, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.