Tyrosinase (TYR) Mouse Monoclonal Antibody [Clone ID: LBI1F3]
Product Specifications
Background
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]
Overview
Carrier-free (BSA/glycerol-free) TYR mouse monoclonal antibody, clone LBI1F3
Synonyms
ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3
Gene Name
Homo sapiens tyrosinase (TYR), mRNA.
Gene ID
7299
UniProt
P14679
Conjugation
Unconjugated
Related Pathways
Melanogenesis, Metabolic pathways, Riboflavin metabolism, Tyrosine metabolism
Field of Research
Melanogenesis, Metabolic pathways, Riboflavin metabolism, Tyrosine metabolism
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
TYR
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7299
Uniprot URL
https://www.uniprot.org/uniprot/P14679
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