NM23A (NME1) Mouse Monoclonal Antibody [Clone ID: LBI22F10]
Product Specifications
Background
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]
Synonyms
AWD; GAAD; NB; NBS; NDKA; NDPK-A; NDPKA; NM23; NM23-H1
Gene Name
Homo sapiens NME/NM23 nucleoside diphosphate kinase 1 (NME1), transcript variant 1, mRNA.
Gene ID
4830
UniProt
P15531
Conjugation
Unconjugated
Related Pathways
Metabolic pathways, Purine metabolism, Pyrimidine metabolism
Field of Research
Metabolic pathways, Purine metabolism, Pyrimidine metabolism
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Stem cell - Pluripotency
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NME1
Overview
Carrier-free (BSA/glycerol-free) NME1 mouse monoclonal antibody, clone LBI22F10
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4830
Uniprot URL
https://www.uniprot.org/uniprot/P15531
Curated Selection
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