P95 NBS1 (NBN) Mouse Monoclonal Antibody [Clone ID: LBI1G10]
Product Specifications
Background
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
Synonyms
AT-V1; AT-V2; ATV; NBS; NBS1; P95
Gene Name
Homo sapiens nibrin (NBN), transcript variant 1, mRNA.
Gene ID
4683
UniProt
O60934
Conjugation
Unconjugated
Related Pathways
Homologous recombination
Field of Research
Homologous recombination
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NBN
Overview
Carrier-free (BSA/glycerol-free) NBN mouse monoclonal antibody, clone LBI1G10
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4683
Uniprot URL
https://www.uniprot.org/uniprot/O60934
Curated Selection
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