NFH (NEFH) Mouse Monoclonal Antibody [Clone ID: LBI10A7]

Product Specifications

Background

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]

Overview

Carrier-free (BSA/glycerol-free) NEFH mouse monoclonal antibody, clone LBI10A7

Synonyms

NFH

Gene Name

Homo sapiens neurofilament heavy chain (NEFH), mRNA.

Gene ID

4744

UniProt

P12036

Conjugation

Unconjugated

Related Pathways

Amyotrophic lateral sclerosis (ALS)

Field of Research

Amyotrophic lateral sclerosis (ALS)

Dilution

WB 1:2000, IHC 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.