NFH (NEFH) Mouse Monoclonal Antibody [Clone ID: LBI10A7]
Product Specifications
Background
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
Synonyms
NFH
Gene Name
Homo sapiens neurofilament heavy chain (NEFH), mRNA.
Gene ID
4744
UniProt
P12036
Conjugation
Unconjugated
Related Pathways
Amyotrophic lateral sclerosis (ALS)
Field of Research
Amyotrophic lateral sclerosis (ALS)
Dilution
WB 1:2000, IHC 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NEFH
Overview
Carrier-free (BSA/glycerol-free) NEFH mouse monoclonal antibody, clone LBI10A7
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4744
Uniprot URL
https://www.uniprot.org/uniprot/P12036
Curated Selection
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